| abstract |
The present invention concerns compounds of formula (A 1 )(A 2 )N—R 1 (I), the N-oxide forms, the pharmaceutically acceptable addition salts, the quaternary amines and stereochemically isomeric forms thereof, wherein R 1 is substituted C 1-6 alkyl; —S(═O)—R 8 ; —S(═O) 2 —R 8 ; C 7-12 alkylcarbonyl; optionally substituted C 1-6 alkyloxycarbonylC 1-6 alkylcarbonyl; with R 8 being C 1-6 alkyl, aryl 1 or Het 1 ; (A 1 )(A 2 )N— is the covalently bonded form of the corresponding intermediate of formula (A 1 )(A 2 )N—H, which is a HIV replication inhibiting pyrimidine of formula |