http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7744851-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_604e07c32377cab416660b10fd8f494c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-04 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate | 2007-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_777eebd0b6dbf2e94ff410933e183f2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f9aee2cf8a9bd07486b4a633355459d |
| publicationDate | 2010-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7744851-B2 |
| titleOfInvention | Methods and agents for preparing 18F-radiolabeled fluorinating agents |
| abstract | The present invention is directed to a method for preparing an anhydrous 18 F-radiolabeled fluorinating agent by a nucleophilic reaction of a hydrated 18 F-radiolabeled fluoride ion source with an unsaturated carrier compound; treating the 18 F-radiolabeled carrier compound to produce a non-aqueous mixture of the 18 F-radiolabeled carrier compound in a solvent; and reacting the 18 F-radiolabeled carrier compound with a nucleophilic composition in a nucleophilic reaction to produce an anhydrous 18 F-radiolabeled fluorinating agent. The present invention is also directed to an anhydrous 18 F-radiolabeled fluorinating agent comprising the formula [Q n M] x+ ( 18 F − ) x . Additionally, the present invention is directed to an 18 F-radiolabeled fluorinated radiopharmaceutical or an 18 F-radiolabeled fluorinated radiotracer prepared by reacting the anhydrous 18 F-radiolabeled fluorinating agent with a drug intermediate. The present invention is further directed to methods for treating a disease or imaging a subject using an 18 F-radiolabeled fluorinated radiopharmaceutical or an 18 F-radiolabeled fluorinated radiotracer. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10468722-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010243972-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8641903-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11242314-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10720666-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11398645-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11707538-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11069921-B2 |
| priorityDate | 2006-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 242.