Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4dbc89ac239072e0a4848405f05a5e9c |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C221-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C221-00 |
filingDate |
2008-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2010-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_861907a139ebf84985d938fd2aa21e12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99989b2b02b22a0863f49acdeb12f94a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cc2c925b273c38ac603ae3b34c20560 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52b975c0c17017cca90c5b26c39eee7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e602a52f998b87de177b24d387f52ab5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9933260dfbe7b6f8f52c45ab0323a347 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c293096ed98c163d5267c4c10ba3bbb2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50d3aa1f8adb53a9904bf59c04c75a13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a49e9c74940d2d2aa79d3b00f970f8aa |
publicationDate |
2010-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7737302-B2 |
titleOfInvention |
Process for preparing bupropion hydrochloride |
abstract |
This invention described a synthesis method of bupropion hydrochloride. m-chloropropiophenone was brominated directly with bromine, then aminated with t-butylamine and finally reacted with HCl to obtain crude product of bupropion hydrochloride. Pure product was obtained after recrystallization. This method is convenient and suitable for commercial manufacturing because of low cost of production, high yield, less byproducts and being environmental friendly. |
priorityDate |
2007-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |