Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c22c6d06e5563aee18cc3c610cfa6180 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5443 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-54 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20 |
filingDate |
2005-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2010-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9eededea01b1b020aed7c35113c4428c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cea777a08de358c944accd70dc0dc27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea8ec3c48c7d3ef467589e1b5361b466 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37900313ce5300a8f15b594656381d88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ced10d4e4981ebb9522df3719809609 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_577f44eba65864ead1c4acea4289c7c1 |
publicationDate |
2010-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7736638-B2 |
titleOfInvention |
Interleukin-15 antagonist peptide |
abstract |
Current invention is related to the molecular pharmacology branch particularly to a peptide belonging to the Interleukin-15 sequence (IL-15) which is able to inhibit IL-15 biological activity, analogues or mimetic of such peptides. In the current invention it is shown that the peptide inhibits both IL-15-induced T cells proliferation upon binding to the IL15 receptor a subunit (IL15Rα) and TNFα-mediated apoptosis. n Besides, this invention is related to the use of this peptide in the treatment of several pathologies where aberrant IL-15 or IL-15Rα expression is associated to the disease progression. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10865226-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11518785-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020148721-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11278505-B2 |
priorityDate |
2004-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |