abstract |
A compound of formula (I) n nwhere one of A 1 , A 2 or A 3 is N, and the others are independently selected from CH or N; ring B is a fused 5 or 6-membered carbocyclic or heterocyclic ring which is optionally substituted as defined in the specification, and R 1 , R 2 , R 3 , R 4 , and n are as defined in the specification.n n The compounds are inhibitors of EphB4 or EphA2 and therefore may be useful in pharmaceutical compositions for the treatment of conditions such as cancer. |