http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7696351-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b4a80ac02f1ecd0e698ec665e9b36b6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 |
filingDate | 2006-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2010-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef2f35dde9247b633277856b8a39acdd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_529f613f7ffa3d8ffe98555f31318f4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5510da7fd2e392466698efa3d1b9d42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51947de41e37b43b416201aa2b94135d |
publicationDate | 2010-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7696351-B2 |
titleOfInvention | Process for the preparation of S-(+)-clopidogrel by optical resolution |
abstract | The present invention relates to a process for the preparation of S-(+)-clopidogrel by an optical resolution and, more particularly, to a process for the preparation of S-(+)-clopidogrel represented by the following formula 1 with high optical purity by converting a clopidogrel racemic carboxylic acid into a diastereomeric salt using a (+)-cinchonine for optical resolution, extracting an S-(+)-clopidogrel carboxylic acid from the diastereomeric salt using a suitable solvent under an acidic condition and then reacting the S-(+)-clopidogrel carboxylic acid with methanol. |
priorityDate | 2005-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 168.