Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8a9982b1666c54b5bf02d6c944891e4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-726 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
filingDate |
2005-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2010-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d3d6b5efe1d9ada159e829c66346b2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd154ad524639c654097d47d6d01b245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_064a172d564eee3480c690138b5a9506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3147144c19ef1bc8acfa5a8d942db7ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33ebcdaeadc310e10b17210b07375f63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50ac11eddc363715ee8fa464fdddbe2b |
publicationDate |
2010-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7682802-B2 |
titleOfInvention |
Assay solution compositions and methods for GPCR arrays |
abstract |
Buffered assay solutions for performing 1) binding or 2) functional assays on GPCR arrays, along with methods for their use are described. The buffered assay solution has an underlying composition having: a buffer reagent with a pH in the range of about 6.5 to about 7.9; an inorganic salt of either a monovalent or divalent species, at a concentration from about 1 mM to about 500 mM; and optionally a combination of: c) a blocker reagent at a concentration of about 0.01 wt. % to about 2 wt. % of the composition, or d) protease-inhibitor at a concentration of about 0.001 mM to about 100 mM. In an embodiment for functional assay uses, the composition is modified to also include a GTP-analogue, a guanosine 5′-diphosphate (GDP) salt, and/or an anti-oxidant reagent. |
priorityDate |
2003-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |