| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7e0e42cba4bee6c48312821708b5d3a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B2307-7145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B2307-714
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-31906
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B2307-554
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B2307-552
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B2250-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B2307-728
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-31667
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2383-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-31663
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B2535-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B27-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J7-056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B27-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B27-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B27-302
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B27-283
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B27-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B27-308
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B32B27-42 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B32B25-20 |
| filingDate |
2006-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42dfb95cddad7bc8fb87b36249898833
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6aace9ae60d566eebf2b4c71729844a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79fa1d215edb367a151348833ec35beb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e2d4a4b3647a9810a762131282e1ac0 |
| publicationDate |
2010-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7670686-B2 |
| titleOfInvention |
Long-term hydrophilic modification of PDMS substrate and method for manufacturing the same |
| abstract |
The present invention relates to a hydrophilic surface structure of the non-hydrophilic substrate and the manufacturing method for using the same. The hydrophilic substrate surface structure is fabricated by forming an amphiphilic polymer layer, a cross-linked stacking layer, and a hydrophilic layer in sequence on the surface of a non-hydrophilic substrate. For example, the hydrophobic surface of poly(dimethylsiloxane) (PDMS) can be made from hydrophobic to hydrophilic and the hydrophilicity can be retained for a long period of time and resist protein adsorption. The hydrophilic thin films give long term stability to the PDMS surface by resisting hydrophobicity recovery, which is the major problem with PDMS. The disclosed method can further be used in the immobilization of protein and other molecules. This method can also be used for modifying other substrates which suffer problems of surface instability. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9920170-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10160838-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10233290-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10711108-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10233289-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9920171-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10233293-B2 |
| priorityDate |
2005-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |