| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a722744e77c81c5f5cf415087e2ee92b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0042
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4064
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-1075 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6456
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0059
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0058
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0041
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0056 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-107 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B10-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B6-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 |
| filingDate |
2001-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_237a66b9c737518a8a5de44836f71a0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b6bc8ffab81653c715a03eaee1a7540
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b93c27c86f6f00a126a2080b67aaa66f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da5ea049df78b30a33a3197304142da1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_966efc5bb5166f16998b7e0b372ef320 |
| publicationDate |
2010-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7668586-B2 |
| titleOfInvention |
In vivo multiphoton diagnostic detection and imaging of a neurodegenerative disease |
| abstract |
The present invention is directed to a method of detecting a neurodegenerative disease in a mammal by activating brain tissue of the mammal by application of radiation under conditions effective to promote a simultaneous multiphoton excitation of the brain tissue and to emit a fluorescence characteristic. The fluorescence characteristic is then compared to a standard fluorescence emitted by exciting healthy brain tissue of the mammal under the same conditions used to carry out the activating step. Brain tissue where the fluorescence characteristic differs from the standard fluorescence is identified as potentially having a neurodegenerative disease. Another aspect of the present invention is directed to a method of producing an image of brain tissue from a mammal by activating brain tissue of a mammal with radiation applied under conditions effective to promote a simultaneous multiphoton excitation of the brain tissue and to produce fluorescence. The fluorescence is then collected to produce an image of the brain tissue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012035444-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8346345-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009185980-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10394008-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10018817-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8873827-B2 |
| priorityDate |
2000-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |