http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7666640-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d5d546aa6cbfb52c137af7cafc36bf4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9019c0ce5cb7b82c85e121f6cac86dce |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 |
filingDate | 2009-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2010-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33410e0568a263b2e2b98bb06a9ea866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbced729e34be031dcc8416ba88cdf95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0951fc34f512dc1bd95ce6155776a35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7d794e789c32571ed5c8a7a4038381f |
publicationDate | 2010-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7666640-B2 |
titleOfInvention | DNA sequences for the expression of alloproteins |
abstract | The present invention discloses an expression method for non-naturally-occurring amino acid-containing protein comprising: expressing in animal cells: (A) a mutant tyrosyl-tRNA synthetase that is a mutation of tyrosyl-tRNA synthetase originating in E. coli with an enhanced specificity for a non-naturally-occurring tyrosine derivative as compared with the specificity for tyrosine; (B) suppressor tRNA originating in Bacillus species, Mycoplasma species or Staphylococcus species of eubacteria and capable of binding with the tyrosine derivative in the presence of the mutant tyrosyl tRNA synthetase; and, (C) a desired protein gene that has undergone a nonsense mutation at a desired site; wherein, the tyrosine derivative is incorporated at the location of this nonsense mutation. |
priorityDate | 2002-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.