http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7659363-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1542e8802a0e6a7a8a7c6bd5627eb857 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 |
| filingDate | 2006-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c18db16eb80b60cc517237a652c8b6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2795764323ac682a2ef1388e144881ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76c2622dffb81894fc818ba367dee4ef |
| publicationDate | 2010-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7659363-B2 |
| titleOfInvention | Process for the preparation of insulin or an insulin derivative in the presence of oxygen |
| abstract | The present invention comprises a process for preparing insulin or an insulin derivative with correctly linked cysteine bridges from a precursor of said insulin or insulin derivative, wherein said precursor is subjected to a folding process in the presence of cysteine or cysteine hydrochloride and a chaotropic auxiliary compound. The insulin or insulin derivative with correctly linked cysteine bridges is obtained by enzymic cleavage by means of trypsin or a trypsin-like enzyme and, where appropriate, additionally by means of carboxypeptidase B and subsequent purification on an adsorber resin, which process is carried out at varied pH and temperature ranges. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017040363-A1 |
| priorityDate | 2004-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 300.