http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7659275-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 |
| filingDate | 2006-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2010-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5efc5353787c2b28c613c96c90504786 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e42e08714af786f68aa8ce053da91f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64c64a58f0688333e28a2be9465c3a98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9268fc550f09289ffb515cf01de0a4c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_083cbf977d7a39c313723e3afc8a22a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf803be6567e682e0d229d0f83b7a964 |
| publicationDate | 2010-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7659275-B2 |
| titleOfInvention | Piperidinyl piperazine derivatives useful as inhibitors of chemokine receptors |
| abstract | In its many embodiments, the present invention provides a novel class of compounds of structural formula IA or IB where R 1 -R 8 are as disclosed herein n nas inhibitors of the CCR5 receptors, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with CCR5 using such compounds or pharmaceutical compositions. The invention also relates to the use of a combination of a compound of this invention and one or more antiviral or other agents useful in the treatment of Human Immunodeficiency Virus (HIV). The invention further relates to the use of a compound of this invention, alone or in combination with another agent, in the treatment of solid organ transplant rejection, graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis. |
| priorityDate | 2005-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 879.