| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0853f14a64b16d1710f4315d150da980 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C10G-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 |
| filingDate |
2005-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2010-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_884a8e16c9895805f0dab0a657670a54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbb35cde9e62c78485af16446044d96e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_829eb396b7aa7d1af373f6830416e52f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfd517d0ec974af93c6b65347ff6ef20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c4efbeac25fbf12286a50d190d8871c |
| publicationDate |
2010-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7642063-B2 |
| titleOfInvention |
Methods for targeting and killing glioma cells |
| abstract |
A diagnostic technique for matching anti-cancer peptide drugs to the molecular profiles of individual cancer tumors, and a method using the technique for a patient-specific treatment of tumors in mammals. This strategy matches anti-cancer peptide drugs to the molecular profiles of individual tumors, and includes the development of two banks, both of which use the same targeting peptides. Targeting peptides are identified using biopsies or other tissue materials from multiple cancer patients and placed into two banks. For a bank of probes, targeting peptides are linked to a label such as a fluorescent or a radioisotope. For a bank of drugs, targeting peptides are linked to a cytotoxic peptide to form a “targeting peptide drug”. Peptide probes are used to establish molecular profiles of individual tumors. Based on these molecular profiles, a patient-specific combination of targeting drugs from the bank of peptide drugs is prepared and the patient is treated. Any currently used cytotoxic agent that can be linked to targeting peptides may be used in place of cytotoxic peptides. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10172910-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10183058-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11628202-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10532081-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11666624-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10335453-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9243035-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015148303-A1 |
| priorityDate |
2004-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |