http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7629482-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b4f16ad70ddfeb0b838c113aaae408a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-188 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-10 |
| filingDate | 2008-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86f298c66882cff926861cd940ead4a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae913d1fe3e4f1d66f0e8401fe017726 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e281536d0b4fc5374dfb2d4e10ab0d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e80107e622dc5b02541d1931f76e81b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17702ed31f6cf5e0bc823c0057bdf992 |
| publicationDate | 2009-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7629482-B2 |
| titleOfInvention | Process for preparation of cefprozil intermediate |
| abstract | The present invention relates to a process for preparing a key intermediate of cefprozil and use of this intermediate in the preparation of cefprozil thereby avoiding impurity-causing self-acylation. n [R-(Z)]-[4-hydroxy-α-[(3-methoxy-1-methyl-3-oxo-1-propenyl)amino]] benzeneacetic acid, mono potassium salt is reacted with ethyl chloroformate to obtain mixed anhydride which is then silylated with N,O-bis(trimethylsilyl)acetamide. The silylated compound obtained is reacted with [7-trimethylsilylamino-3-(Z/E-propen-1-yl)-3-cephem-4-carboxylic acid]trimethylsilyl ester and deprotected with aqueous hydrochloric acid to give cefprozil. |
| priorityDate | 2004-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 164.