Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4753 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-193 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 |
filingDate |
2002-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2009-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f327eee921dbc5c67b594b6c331d8511 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f1a6c2e25235f2b6f08a0418073c205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3d3314d81783f1756f0ddbf3292762a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5530e2658b5324ac0600c1c83ca9ac6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52609cada76e170ddd54e59426ed0180 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1a9d688670344f32a8c36c73276e2ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4365ac57cfd3de3b39626c2d7db602d |
publicationDate |
2009-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7605127-B2 |
titleOfInvention |
Truncated hepatocyte growth factor variant protein HGF/NK2 |
abstract |
The present invention relates to a novel truncated form of heptocyte growth factor (HGF) which specifically antagonizes the activity of HGF and to a novel truncated form of HGF that is a partial HGF agonist. In particular, the present invention relates to the purification, molecular cloning, recombinant expression of the truncated HGF variants and related pharmaceutical compositions. The present invention further relates to the utilization of the small HGF variants to either inhibit HGF mitogenesis or stimulate HGF mitogenesis in cells expressing the receptor for HGF. |
priorityDate |
1990-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |