| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d7740cdf569a00038ad04686c272a19 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 |
| filingDate |
2006-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ef7306b3c973ad4eb607593a64e33be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_099b1e5b615ed0d8ee12c0b763865d64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41c7d25248d5d02ba8c18869b7caef28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2097f1d01cf5a485a2d1526b342b793
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b64c72b5f9e3a1c782101f9bc5c896ee |
| publicationDate |
2009-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7592367-B2 |
| titleOfInvention |
Compounds from Garcinia hanburyi, their use in treating cancer and method of separating epimers thereof |
| abstract |
Three pairs of C-2 epimeric xanthones isolated from Garcinia hanburyi and method for efficiently separating the xanthone compounds into individual epimers, each of which possesses varying biological effects. The compounds are useful for their anticancer effects, particularly because they are shown to be non-substrates of the multidrug-resistance transporter. Some of the epimers have significant inhibitory effects on cytochrome P450 systems. The xanthone compounds of the present invention are gambogic acid, epigambogic acid, isogambogic acid, isoepigambogic acid, 30-hydroxygambogic acid and 30-hydroxyepigambogic acid. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102796113-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102796113-A |
| priorityDate |
2005-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |