Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0362 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70567 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-00 |
filingDate |
2006-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2009-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81e2b2839d63c6b52b946fde5b0434b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2770c1f65870ce72b68a5364a2b5c9ed |
publicationDate |
2009-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7586021-B2 |
titleOfInvention |
Nucleic acid construct, metabolic disordered non-human animal and use thereof |
abstract |
The present invention provides a transgenic non-human animal comprising a human-derived LXRα mutant gene to express a human LXRα mutant protein, wherein the human LXRα mutant is an isoform of LXRα involved in inhibition of normal cholesterol metabolism by normal LXRα; a nucleic acid construct which can be used to produce the transgenic non-human animal; and use thereof. |
priorityDate |
2005-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |