| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a3584f154a96f106613dfceb75b5ca8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-815
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
| filingDate |
2008-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ccd4392ac8268f28a3667c2cd101b1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8231e1f80f6d502647a4a5caac1b375f |
| publicationDate |
2009-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7582727-B1 |
| titleOfInvention |
Pharmaceutical formulations of bivalirudin and processes of making the same |
| abstract |
Pharmaceutical batch(es) or pharmaceutical formulation(s) comprising bivalirudin as the active ingredient, and a method of preparing the pharmaceutical batch(es) or pharmaceutical formulation(s). The pharmaceutical batch(es) or pharmaceutical formulation(s) may have a maximum impurity level of Asp 9 -bivalirudin that does not exceed about 0.6%. Also, the pharmaceutical batch(es) or pharmaceutical formulation(s) may have a reconstitution time that does not exceed about 42 seconds. The method of preparing the pharmaceutical batch(es) or pharmaceutical formulation(s) may comprise dissolving bivalirudin in a solvent to form a first solution, efficiently mixing a pH-adjusting solution with the first solution to form a second solution in which the pH-adjusting solution may comprise a pH-adjusting solution solvent, and removing the solvent and the pH-adjusting solution solvent from the second solution. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3206705-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015175668-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7985733-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE46830-E
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108567746-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104888207-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111265486-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104888207-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111388657-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111388657-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2730000-C1 |
| priorityDate |
2008-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |