| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-01 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-001 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate |
2006-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d84a0a9079f441bf2a7465f5055e4320
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09845d71cb38c28a98cf49000304573a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56ceb98d749bade8babe242b4b01f069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c36c2c865b7a925998b4747d5b109b5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b78a961204a39d791f822a034f1b1fb2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_244af5ad96cd463be5ffee829e7d03cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddac9d3b5bcaf36b8cf1fc1135819ebe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff7d7053a70486bf58ca57587301a007 |
| publicationDate |
2009-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7582468-B2 |
| titleOfInvention |
Process for preparing (2R,3S)-1,2-epoxy-3-(protected)amino-4-substituted butane and intermediates thereof |
| abstract |
The present invention relates to a process for preparing (2R,3S)-1-halo-2-hydroxy-3-(protected)amino-4-substituted butane comprising contacting a mutagenized Rhodococcus erythropolis having ATCC deposit no. PTA-6648 with (3S)-1-halo-2-oxo-3-(protected)amino-4-substituted butane substrate. The present invention also relates to a process comprising mixing (2R,3S)-1-halo-2-hydroxy-3-(protected)amino-4-substituted butane with at least one base in the presence of at least one solvent to produce a reaction mixture containing (2R,3S)-1,2-epoxy-3-(protected)amino-4-substituted butane. The present invention further relates to a process comprising crystallizing the (2R,3S)-1,2-epoxy-3-(protected)amino-4-substituted butane out of the reaction mixture by concurrently adding water and the reaction mixture together. The present invention is also directed to a mutagenized Rhodococcus erythropolis having ATCC deposit no. PTA-6648. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11193157-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9029112-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010183716-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010183715-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010178339-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010178340-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10604781-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8796002-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9404092-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9714439-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10196667-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9394551-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9080192-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9296992-B2 |
| priorityDate |
2005-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |