http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7579476-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b9010c96091a18c7c610e4b970b543d |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
filingDate | 2006-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e898369bb99832a1fce2843a07e8457f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_601d516323953bb7f985d2e7cba6b9db |
publicationDate | 2009-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7579476-B2 |
titleOfInvention | Transition metal mediated oxidation of hetero atoms in organic molecules coordinated to transition metals |
abstract | The present invention is directed to a process for the catalytic oxidation of the thioether 5-methoxy-2-((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)methylthio)-1H-benzimidazole to its sulfoxide: 5-methoxy-2-((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)methylsulfinyl)-1H-benzimidazole comprising: reacting the thioether with: 1) a transition metal catalyst; and, 2) an oxygen source; wherein the thioether is oxidized to a sulfoxide and wherein one of either the R and S enantiomers is formed to an enantiomeric excess. |
priorityDate | 2006-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 330.