| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-16 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C403-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-05 |
| filingDate |
2003-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7db6f82fb6270b871b251d7ef79cdf6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5ce0006119007637937e3266ee393f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f8ac2e4567d7fec50d22d6a99b8c924
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b23bdd5c271354396af2f0efcf6b7604
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cc10f5ccadc406eae6c639bc2ca50bd |
| publicationDate |
2009-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7550510-B2 |
| titleOfInvention |
Solid phase synthesis of arylretinamides |
| abstract |
A solid phase synthetic method for preparing arylretinamides is provided. The method comprises reacting hexachloroacetone with a solvent-suspended resin-bound triphenylphosphine to provide a suspension comprising an activated chlorinating reagent; reacting retinoic acid with the activated chlorinating reagent to provide retinoyl chloride; adding pyridine and a select arylamine to the resulting mixture; and stirring the resulting mixture for a time and at a temperature sufficient for the select arylamine to react with the retinoyl chloride and provide the arylretinamide. Also provided, are select arylretinamides that can be prepared by the present method, and methods of using such arylretinamides to induce apoptosis in cancer cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11020334-B2 |
| priorityDate |
2001-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |