http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7538245-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7995660796c354a2881371a7406bf6dd |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06139 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-078 |
filingDate | 2004-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b27df22778ec0d96df9baf6419166bb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e05873d94eb46ac83ac95028f8818a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32125f46ecd00c7dce4e8d6327fb9b28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afc053b10cae109bbb771f158b803744 |
publicationDate | 2009-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7538245-B2 |
titleOfInvention | Process for the manufacture of an enantiopure compound |
abstract | Process for the manufacture of an enantiopure compound comprising at least one functional group capable of reacting with an activated carboxyl group, starting from a mixture of enantiomers of the said compound, in which process: (a) a reaction medium comprising the mixture of enantiomers and a reagent based on an enantiopure amino acid, in which reagent at least one amino group of the amino acid is protected by a protective group and in which reagent at least one carboxyl group of the amino acid is activated, is subjected to conditions appropriate for bringing about the reaction of the functional group capable of reacting with the activated carboxyl group with the activated carboxyl group, so as to form a carbonyl bond; (b) the mixture of diastereomers obtained is subjected to a separation operation, so as to obtain at least one fraction composed essentially of a diastereomer, (c) at least a portion of the said fraction is subjected to a stage of cleavage of the carbonyl bond under conditions under which the protective group is essentially stable; and (d) the enantiopure compound and an enantiopure derivative of the amino acid in which at least one amino group is protected by the protective group are recovered. |
priorityDate | 2003-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 485.