http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7524925-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60165f3403b3b7f379f262fe11bd3909 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-13 |
| filingDate | 2005-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2009-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c98ab698db59f0d0a8662290e78673af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_570bffe456fce17f8febcadaed81bf0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af29541b4c560642de23265ff17fccdb |
| publicationDate | 2009-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7524925-B2 |
| titleOfInvention | Protein interaction reporter agents and methods for using same |
| abstract | Particular aspects provide novel protein interaction reporter (PIR) compounds (e.g., formulas I and II), comprising at least two protein reactive moieties (e.g., N-hydroxysuccinamide), each linked to a reporter moiety (e.g., mass reporter) by a covalent labile bond that is differentially cleavable with respect to peptide bonds (e.g., by a method such as collisional activation in a mass spectrometer, activation by electron capture dissociation (ECD), photoactivation, etc.), wherein the reporter moiety is operatively releasable from the PIR agent upon cleavage of the labile bonds, the released reporter moiety having a characteristic identifying property or label (e.g., m/z value). Particular PIRs comprise a mass reporter moiety, and further comprise an affinity group, (e.g., biotin), linked to the PIR (e.g., to the mass reporter moiety) by a selectively cleavable bone (e.g. photo-labile bond)). Additional aspects provide methods for characterizing intermolecular or intramolecular protein interactions using one or more inventive PIR compounds. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9612246-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014349871-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009159842-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010047814-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9139614-B2 |
| priorityDate | 2004-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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