| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5e3b3f97b97d7915f950984a3e2810c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-52 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
| filingDate |
2001-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4a630b661b26e9d2d5b2d922088fcae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_792a986fe960afc1c7b5b130f278a03f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d049696e847eb38c8e2ffda6fd5f1a3 |
| publicationDate |
2009-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7524826-B2 |
| titleOfInvention |
Method of inhibiting the generation of active thrombin on the surface of a cell within an atherosclerotic plaque |
| abstract |
The present invention provides methods for preventing the generation of active thrombin on the surface of cells. The present methods are based upon the surprising discovery that expression or activation of an ER resident chaperone protein in a cell inhibits the generation of thrombin on the surface of the cell. Accordingly, expressing or activating an ER resident chaperone protein can be used to treat or prevent any of a number of thrombotic diseases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008026365-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007009710-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7723500-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8809006-B2 |
| priorityDate |
2000-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |