| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1350f07069ebabbb3ca5213425d5bbec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_404ad3939c28be90e799904b88ef1f06 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-22022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-35 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
| filingDate |
2008-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42a904536dbb9d7b6f2188d7812ead94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3444de3cdcc368ff04a83482104f531b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c7f5059892d841043fde81506ef8659
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e43ceb6bbea1317fdc91d3b473779397
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_479eb1b43595b1f3733eb98b587210ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_143197459839288ec59d312a060ce208 |
| publicationDate |
2009-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7524648-B2 |
| titleOfInvention |
Expression system for enhancing solubility and immunogeneicity of recombinant proteins |
| abstract |
Expression system for enhancing solubility and immunogenicity of recombinant proteins. The expression system includes a protein expression vector that contains a chimeric gene encoding a chimeric protein. The chimeric protein contains three polypeptidyl fragments: (a) a first polypeptidyl fragment at the N-terminal end of the chimeric protein that contains a protein transduction domain (PTD) or a fragment thereof having HIV Tat PTD activity; (b) a second polypeptidyl fragment at the C-terminal end of the first polypeptidyl fragment that contains a J-domain or a fragment thereof having heat shock protein 70 (Hsp70)-interacting activity; and (c) a third polypeptidyl fragment at the C-terminal end of the second polypeptidyl fragment that contains a target protein or polypeptide. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010016221-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8470972-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8541550-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8507277-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8927691-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009208478-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8952133-B2 |
| priorityDate |
2007-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |