http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7514580-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-16 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-48 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C61-22 |
filingDate | 2005-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_839ca7b32c058699fe23dd49c37dfc48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_debdd8a6da72d8fee7ad041bf20f6835 |
publicationDate | 2009-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7514580-B2 |
titleOfInvention | Process for the preparation of 4,5-diamino shikimic acid derivatives |
abstract | The present invention relates to a process for the preparation of a 4,5-diamino shikimic acid derivative of formula n nand pharmaceutically acceptable addition salts thereofn nwhereinn R 1 , R 1′ are independent of each other H or alkyl, R 2 is an alkyl and R 3 , R 4 are independent of each other H or an alkanoyl, with the proviso that not both R 3 and R 4 are H. 4,5-diamino shikimic acid derivatives of formula I, especially the (3R,4R,5S)-5-amino-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-ene-carboxylic acid ethyl ester and its pharmaceutically acceptable additional salts are potent inhibitors of viral neuraminidase. |
priorityDate | 2004-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 454.