| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb947f71d9719e3f5cb9c0c5dbbe6e77 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-366
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2007-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_227389db6fe45a14917167a1c8dc88db
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fe3688c6fb36432e0de528e4ad16266 |
| publicationDate |
2009-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7501114-B2 |
| titleOfInvention |
Ex vivo and in vivo expression of the thrombomodulin gene for the treatment of cardiovascular and peripheral vascular diseases |
| abstract |
The present invention relates to methods and compositions for treatment of cardiovascular and peripheral vascular diseases using ex vivo and in vivo gene delivery technologies. One aspect of the present invention relates to a method for treating a vascular disease by introducing a DNA sequence encoding a TM protein or its variant into a segment of a blood vessel in vivo using a gutless adenovirus vector. Another aspect of the present invention is to provide a method to deliver a gutless adenovirus vector carrying a DNA sequence encoding a TM protein or its variant using a stent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8236300-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7803365-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009123440-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8367056-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009238795-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009105180-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9353383-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9388427-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007238685-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7687058-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011307076-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011196022-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011196023-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8048410-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010247487-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7713522-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010240740-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8420075-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8242095-B2 |
| priorityDate |
2002-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |