| abstract |
A potassium channel opener including a compound (e.g., pimaric acid) represented by the formula [I]: n nwherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 are each independently hydrogen, alkyl, alkenyl, halogen, hydroxy, halogenated alkyl, hydroxyalkyl, aminoalkyl, alkoxy, aryl, heteroaryl, acyl, carboxyl, alkoxycarbonyl, hydroxamate, sulfo, carbamoyl, sulfonamide, aldehyde, or nitrile; or R 4 and R 5 may be bonded to each other to form a ring; or R 6 and R 7 may be bonded to each other to form a ring; and all of three bonds represented by are single bonds, or one of the three bonds is double bond and the other bonds are single bonds, or a physiologically acceptable salt thereof as an effective ingredient. |