| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39aeec7b8395418299b3f6e60aa6d518
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76520b0d8d7559ff295393c320ca4826
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac4483b059852e11ae5434b857f8d74e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aef72ff0d469517e06116ffb35dd602b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd72611e8c2f601b56790675d5d3d6ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_922babb6a418c90456423bb947589c63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382c4e1a704775387afb0a9534f22669
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad53c30973107812d5e6e7b229fcd5dd |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-10001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N31-00 |
| filingDate |
2004-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6af4136886287f3fa13e2996ff46ea91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d7c01def867c40165261f7e097d3d04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f2c624833264404e196289dc2dc4dfe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf547d704c9c18502f06942351346dfb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83690c1752642af0e865ebb699ffffe4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f775e1245e49e155e624745d54f8d4a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_064295417a58cc8a2fa4a2bd7317bde4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7215c90e2e9e92c7633b5e7d80f6934 |
| publicationDate |
2009-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7494795-B2 |
| titleOfInvention |
Crystal structure of FMS-like tyrosine kinase |
| abstract |
The invention relates to FMS-like tyrosine kinase (FLT3), FLT3 binding pockets or FLT3-like binding pockets. The invention relates to a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. The invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. The invention relates to methods of using the structure coordinates to screen for and design compounds that bind to FMS-like tyrosine kinase protein, complexes of FMS-like tyrosine kinase protein, homologues thereof, or FLT-3-like protein or protein complexes. The invention also relates to crystallizable compositions and crystals comprising an FMS-like tyrosine kinase cytoplasmic domain or homologues thereof. The invention also relates to methods of identifying inhibitors of the cytoplasmic domain of FMS-like tyrosine kinase protein. |
| priorityDate |
2003-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |