| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f79749e86afce9444a364ab60ca3584 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C247-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-11 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-04 |
| filingDate |
2005-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2009-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a1188198b3ec2d0826151cb036a1904
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0ce14f03a27235717f4237e7857e460
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_510aecd5343d17ab622606343d08aefc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ace0737076e7b92dbb38821539dd78f0 |
| publicationDate |
2009-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7491744-B2 |
| titleOfInvention |
Indoleacetic acid and indenacetic acid derivatives as therapeutic agents with reduced gastrointestinal toxicity |
| abstract |
The presently disclosed subject matter provides derivatives of non-steroidal anti-inflammatory drugs (NSAIDs) that are characterized by substantially reduced cyclooxygenase inhibiting activity, yet retain the ability to interact with and modulate the activities of other polypeptides such as the class of peroxisome proliferators-activated receptors (PPARs) and γ-secretase. Also provided are methods of using the derivatives to treat pathological disorders. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8143302-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11738004-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009118290-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10526307-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10975054-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9895351-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10981886-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010254910-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11407727-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9862698-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2015364696-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7736624-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014371261-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11680073-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11130744-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11104658-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008139449-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11198679-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8865130-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10398678-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8168656-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009252678-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9346803-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11186596-B2 |
| priorityDate |
2004-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |