http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7488466-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0004 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M36-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 |
filingDate | 2002-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9721a7fe3a40d05ca98dfc74f44f4da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b10e1677567da1e3a906f324d6be1900 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_968a46705451c091b42fd603fa86a7c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3102a0aa1b93d76cd0355eac28089833 |
publicationDate | 2009-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7488466-B2 |
titleOfInvention | Preparation for determining pyrimidine metabolic capacity |
abstract | The present invention provide a method for measuring and assessing the capacity in an individual subject to metabolize a variety of fluorouracil drugs, such as 5-fluorouracil, which are degraded in the pyrimidine metabolic pathway, and a preparation useful for the measurement and assessment. The present invention can be carried out by: administering a preparation for determining pyrimidine metabolic capacity comprising as an active ingredient a pyrimidine compound or pyrimidine metabolic compound that acts as a substrate for a pyrimidine metabolizing enzyme, in which at least one of the carbon, oxygen, and nitrogen atoms is labeled with an isotope; and assessing in vivo pyrimidine metabolic capacity based on the behavior of an excreted metabolite. |
priorityDate | 2001-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.