| abstract |
This invention provides 2-aminoquinoline derivatives represented by a general formula [I] n n n n n n n n n n n n [in which R 1 and R 2 either stand for lower alkyl, lower cycloalkyl, etc., or R 1 and R 2 together form an aliphatic nitrogen-containing heterocycle with the nitrogen atom to which they bind; R 3 , R 4 , R 5 , R 6 and R 7 stand for hydrogen, lower alkyl, etc.; R 8 stands for lower alkyl, lower alkyloxy, etc.; and n stands for an integer of 0-4]. The compounds act as melanin concentrating hormone receptor antagonist, and are useful as medicines for central nervous system disorders, cardiovascular disorders and metabolic disorders. |