http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7476654-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7449ca99fbf1c556219fe28876cbf2a9 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 |
filingDate | 2005-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2009-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7bc1ae654c8a24eed8034de73ebb513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e168952642a3cf0a7f8c446004971d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32048bafebc7da07030a7b89c6d2824e |
publicationDate | 2009-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-7476654-B2 |
titleOfInvention | Method for modulating, regulating and/or stabilizing angiogenesis |
abstract | A method of modulating, regulating and/or stabilizing angiogenesis in a mammal in need thereof, in which the PDGF-D level or activity or both in the mammal are modulated or increased. In preferred embodiments, an active PDGF-D polypeptide, or a polynucleotide encoding an active PDGF-D is administered to the mammal, preferably at a location where angiogenesis modulation or stabilization is desired. The PDGF-D is advantageously co-administered with an angiogenic growth factor, such as a member of the VEGF family of growth factors, in particular VEGF-E. The claimed method inhibits leakage of blood vessels and is useful, inter alia, for treatment of edemas. |
priorityDate | 2004-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 317.