Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-66 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-685 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-66 |
filingDate |
2004-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2008-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51c02a94a05b9547777d171c05ff6881 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ec7d1385827afb4c2b9b2b55212bdde http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea6e647ad82b998643bd659b9c5815c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17bac965fdbe5de9b02592cc55434b24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d02c0296e4a9a61c845de249e560320 |
publicationDate |
2008-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7470659-B2 |
titleOfInvention |
Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM) |
abstract |
The present invention addresses the treatment of age-related macular degeneration using regulation of pathogenic mechanisms similar to atherosclerosis. In further specific embodiments, compositions that increase reverse cholesterol transport are utilized as therapeutic targets for age-related macular degeneration. In a specific embodiment, the lipid content of the retinal pigment epithelium, and/or Bruch's membrane is reduced by delivering Apolipoprotein A1, particularly a mimetic peptide. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010047330-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10426817-B2 |
priorityDate |
2001-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |