http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7456296-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_459549086df37b5bed0003502de7e7aa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 |
| filingDate | 2003-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_710256ba1d4dd187fb3448fcf0bd5e8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff5429af211fcd0c14dc545b11a430bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe79f5f18b53e9b72519fbe15353d56c |
| publicationDate | 2008-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7456296-B2 |
| titleOfInvention | Method for preparation of crystalline perindopril erbumine |
| abstract | A process for preparation of crystalline perindopril erbumine of formula (II) n nwhich exhibits the X-ray (powder) diffraction pattern like that shown in FIG. 2 n The process comprises reacting a solution of perindopril of formula (I), n nin a solvent selected from N,N-dimethylformamide, dimethyl acetals of lower aliphatic aldehydes, dimethyl ketals of lower aliphatic ketones and 1,2-dialkoxyethane with tertiary butylamine and crystallization of the erbumine salt thus obtained by heating the reaction mixture to reflux, filtering hot, cooling gradually to 20° C. to 30° C., and further cooling to 0° C. to 15° C. for 30 minutes to 1 hour and finally filtering off and drying the crystals. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009099370-A1 |
| priorityDate | 2003-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 499.