| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_683cccaab594f16358544103539682dc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 |
| filingDate |
2006-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7821076434022930e4aeeb2d1f9f552
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a843ab21518022fd9a6989ca572b08af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab00024699339a63b88fe81497ddd79d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_770949c867598280fd9999a6a5273c2b |
| publicationDate |
2008-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7456011-B2 |
| titleOfInvention |
Modified cyanovirin-n polypeptide |
| abstract |
This disclosure relates to a modified version of cyanovirin-N protein and a transformed Lactobacillus bacterium that is capable of recombinantly expressing this modified protein. Further disclosed are polynucleotide sequence encoding the modified cyanovirin-N protein, expression cassette that allows the expression of the modified protein, and method of make and use of the modified protein as well as the transformed Lactobacillus bacterium. In addition, this disclosure describes two novel promoters originated from L. jensenii , which are capable of directing a high level of gene expression in Lactobacillus bacteria. Also described are an expression cassette comprising one of the novel promoters, a genetically modified Lactobacillus bacterium containing the expression cassette, a method for recombinant gene expression in Lactobacillus bacteria using the novel promoters, and a method for delivery of proteins with desired biological activity to a mucosal surface in a human. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7833791-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009155304-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009148408-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10738338-B2 |
| priorityDate |
2005-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |