http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7427662-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9144728050f5a9e1bea6e76bd30dd761 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate | 2005-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f97276fc48725c675519fc968ebd97bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b01277f142d2d5b8c517b2c9c41c68c |
| publicationDate | 2008-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7427662-B2 |
| titleOfInvention | Inhibition of angiogenesis and destruction of angiogenic vessels by apolipoprotein A-I and high density lipoprotein |
| abstract | Apolipoprotein A-I-rich Lhigh-density Lipoprotein 2 (HDL2) and Apolipoprotein A-I (ApoA-I) was discovered to inhibit angiogenesis in an in vitro human angiogenesis model, the human placental vein angiogenesis model. Apolipoprotein A-I was able to destroy a pre-existing angiogenic response as well as prevent the development of new vessels. Application of Apolipoprotein A-I will be effective in inhibiting tumor growth dependent on angiogenesis, and in decreasing existing blood vessels formed by tumors. It will also be effective in treating non-cancerous diseases which symptoms include an increase in angiogenesis, e.g., psoriasis, retinopathy of prematurity, neovascular glaucoma, diabetic retinopathy, obesity, and psoriasis. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10653747-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9241976-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8568766-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8557767-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9422363-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10208103-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9487575-B2 |
| priorityDate | 2005-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 541.