| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aced62c3f46e2bf7078d9e547e4d1627 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 |
| filingDate |
2004-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfdc9d649ac2b3e048ee06f661cd1838
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8ee97dfee98adc2576c5d5fb16f91dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07dea719fe57fec44c18ec2e7a779285
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3813a723e8045761620244d6880e497d |
| publicationDate |
2008-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7414029-B2 |
| titleOfInvention |
Antagonistic peptides of prostaglandin E2 receptor subtype EP4 |
| abstract |
Antagonistic peptides of prostaglandin E2 receptor subtype EP4 and their use in the treatment or prevention of medical conditions associated with oligouric nephropathy, bone resorption, abnormal intestinal crypt cell proliferation or patency of the ductus arteriosus and the like are provided herein. The antagonistic peptides of the present invention can include the following formula:n nX-A- R n Y m n nwherein “X” is a hydrogen atom or an amine protecting group producing a carbamate or an amide when reacting with the amine; “A” is L-(4,4′)-biphenylalanine or D-(4,4′)-biphenylalanine; “R” is an amino acid selected from the group consisting of threonine, serine, tyrosine, glutamic acid, alanine, leucine and glycine; “Y” is lysine; “n” is an integer ranging from 5 to 7; and “m” is an integer ranging from 0 to 2. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9873719-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010227980-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015148285-A1 |
| priorityDate |
2002-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |