http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7410944-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d55444126b55e1edeb40523a4818da76 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
| filingDate | 2006-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fbf8beef2005d661689978baa27728b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3ac33544234b23317aabf1547ecd012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1c30bb1ac93f37a093e2fa72ae319a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3db477e851645bff45cbc64f7985e676 |
| publicationDate | 2008-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7410944-B1 |
| titleOfInvention | Depression gene |
| abstract | The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human depression predisposing gene, specifically the apoptotic protease activating factor 1 (APAF1) gene, some mutant alleles of which cause susceptibility to depression. More specifically, the invention relates to germline mutations in the APAF1 gene and their use in the diagnosis of predisposition to depression. The invention also relates to the prophylaxis and/or therapy of depression associated with a mutation in the APAF1 gene. The invention further relates to the screening of drugs for depression therapy. Finally, the invention relates to the screening of the APAF1 gene for mutations/alterations, which are useful for diagnosing the predisposition to depression. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015089074-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016134293-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3067359-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015073922-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10561736-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3572513-A1 |
| priorityDate | 2002-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 388.