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filingDate 2005-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2008-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d574265e0933f0297b7df2f42771cd9
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publicationDate 2008-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7402726-B2
titleOfInvention Methods and compositions for screening for modulators of Parkinson's disease
abstract Methods and compositions for identifying an agent (e.g., a gene product or small molecule compound) that modulates a Parkinson's disease phenotype are provided. In practicing the subject methods, a non-mammalian animal model, such as Drosophila melanogaster , that includes a mutant parkin gene and at least one other mutant gene are evaluated for a Parkinson's disease phenotype. Also provided are kits, and systems for practicing the subject methods, as well as methods of use of agents identified in the screening method of the invention.
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