| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99dfdd02bcde8ca0dc96c2777083c0e9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
| filingDate |
2002-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fe2cdc4b1b270515cb38fb901b703b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74d9dae6e418ed666b192e191ed33c5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae8f65dff900ebe0467904eaae947a41 |
| publicationDate |
2008-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7393539-B2 |
| titleOfInvention |
Mycobacterial antigens expressed under low oxygen tension |
| abstract |
A method is provided for identifying mycobacterial genes that are induced or up-regulated under continuous culture conditions defined by a dissolved oxygen tension of up to 10% air saturation measured at 37° C. when compared with a dissolved oxygen tension of at least 40% air saturation measured at 37° C. Said induced or up-regulated genes form the basis of nucleic acid vaccines, or provide targets to allow preparation of attenuated mycobacteria for vaccines against mycobacterial infections. Similarly, peptides encoded by said induced or up-regulated genes are employed in vaccines. In a further embodiment, the identified genes/peptides provide the means for identifying the presence of a mycobacterial infection in a clinical sample by nucleic acid probe or antibody detection. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7632646-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011091881-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8507211-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9005902-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012145491-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010159485-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10786559-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8404826-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8399650-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7901898-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014004151-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9220764-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009082296-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011268744-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009054367-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8003776-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10703784-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011201044-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8017753-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8216795-B2 |
| priorityDate |
2001-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |