Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-0046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D327-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65685 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D327-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 |
filingDate |
2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2008-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e88d1a2fd6de307eb8d11c6c9e13bf30 |
publicationDate |
2008-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7390931-B2 |
titleOfInvention |
Preparation of P-chirogenic phospholanes and their use in asymmetric synthesis |
abstract |
Materials and methods for preparing P-chirogenic monophospholanes and bisphospholanes are disclosed. The methods employ stereoselective cyclization to generate the phospholane rings followed by pyramidal inversion to access a variety of P-chirogenic phospholanes. When bound to transition metals such as rhodium, the disclosed P-chirogenic phospholanes may be used as catalysts in asymmetric synthesis of valuable pharmaceutical chemical entities, including pregabalin. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009304680-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE41920-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2116618-A1 |
priorityDate |
2004-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |