| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93bc8884a8a3d403dcf6dc433f92fed1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-726
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-042 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-507 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 |
| filingDate |
2006-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05b5adbd4c5399059e11ed4d5cd805d4 |
| publicationDate |
2008-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7381523-B2 |
| titleOfInvention |
Methods for identifying compounds for treating diabetes mellitus |
| abstract |
The invention is directed to methods for identifying candidate beta cell-sensitizing compounds comprising providing a pancreatic beta islet cell population derived from a diabetic subject, contacting the beta islet cell population with one or more somatostatin receptor 5-binding compounds, and identifying those somatostatin receptor 5-binding compounds that promote insulin secretion from the pancreatic beta islet cell population at a higher rate than from a control cell population. The invention is further directed to methods for treating type II diabetes comprising administering a beta cell-sensitizing compound identified by the first method of the invention to a diabetic patient in need of treatment. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011178820-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11327931-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10522247-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011145747-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10565170-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9117015-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10915505-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017049010-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9659037-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011152656-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11382507-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8849458-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10456036-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11350822-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8766803-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10437962-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10216767-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010212675-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11060063-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10733154-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011015511-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9918635-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10732173-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10368745-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8532933-B2 |
| priorityDate |
2004-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |