abstract |
The purpose of this invention is:n new selenohydroxy acid compounds and their derivatives; their process for the preparation; use of the new compounds as precursors of L(+)-selenomethionine and/or source of selenium in human or animal nutrition, in cosmetics and pharmaceutics; and nutritional, cosmetic and pharmaceutical compositions containing them. nn The new compounds that are the subject of this invention satisfy the general formula (I): n nin whichn n=0, 1 or 2, R 1 =OH, OCOR 3 , OPO 3 H 2 , OPO(OR 4 )(OR 5 ), or OR 6 , R 2 =OH, R 3 , or NHR 7 , R 3 =particularly alkoxyl (C 1 -C 26 ), ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6a and 6b, S-cysteinyl, or S-glutathionyl, carnitoyl, lipids, polyols, OR 4 =OR 5 =particularly alkoxyl (C 1 -C 26 ), ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6a and 6b, S-cysteinyl, or S-glutathionyl, carnitoyl, lipids, polyols, OR 6 =pyruvate, lactate, citrate, fumarate, maleate, myristate, palmitate, stearate, palmitoleate, oleate, linoleate, natural fatty acids, or 13-cis retinoate, R 7 =H, alkyl, natural amino acids, or natural amines. |