| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e3f238a5ba8eb57a2c1d09f750709088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_021d3c1ca18a495c89afe54a5d8b66b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68aa6aa281c22a9dd83d046816bb85b2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-524
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate |
2001-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc4cb762dd09f20b82764b81d9c73353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c69b972d447287aaad3ca213ff63b9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05cc2bd8ed53829b88c2c7eb08af1c88 |
| publicationDate |
2008-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7371569-B2 |
| titleOfInvention |
Methods for preparing human thrombopoietin polypeptides by mammalian cell cultures |
| abstract |
Procedures to produce a biologically active human TPO by mammalian cells in in vitro cultures are disclosed. Murine myeloma cells were genetically modified by introducing the gene of human thrombopoietin through a DNA construction which includes an immunoglobulin promoter associated to an immunoglobulin enhancer. The hTPO obtained is useful with methods of stimulating proliferation or development of hematopoietic cells of the megakaryocytic leneage in vitro and in vivo. |
| priorityDate |
2000-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |