| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J13-007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J13-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-0052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-001 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 |
| filingDate |
2003-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_feb765dfadc90e2aee18cc2769e7fbaa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2aa4a71b9aef2b0524ecf0a74ab7992a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_525f403c26b88bbc3dbc9fdd57a39dd4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_053fbae343be2e37004bdbc6a67338fc |
| publicationDate |
2008-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-7365218-B2 |
| titleOfInvention |
Process for preparing guggulsterones |
| abstract |
The present invention provides an improved process for the preparation of Guggulsterones which comprises epoxidising 16-dihydropegnenolone acetate (16 DPA) by reacting 16DPA with hydrogen peroxide reagent adduct in the presence of a co-base in a polar solvent to obtain 3 β hydroxy-16 α, 17-oxido-5 pregnen-20-one, converting the 3 β hydroxy-16α, 17-oxido-5-pregnen-20-one by reacting with hydrazine in the presence of a strong base at refluxing temperature followed by oxidation to obtain desired guggulsterones viz. to 5, 17-(20)-cis and trans pregnadiene-3 β, 16-diol of the formula Ia and Ib. |
| priorityDate |
2003-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |