| abstract |
Compounds of the formula I: n nand pharmaceutically acceptable salts thereof wherein X is N, Y is S, Z is —(CR a R b ) r —, A is —NR 3 , m is 2, n is 1, q is 2, R 2 is optioinally substituted aryl or optionally substituted heteroaryl, and p, R 1 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , and R 10 , are as defined herein. The invention also provides methods for preparing, compositions comprising, and methods for using compounds of formula I for treatment of central nervous system diseases. |