| abstract |
A compound of formula: n n n n n n n n n n n n wherein X is a C 2-10 spacer, and R is a substituted or unsubstituted C 6-30 aryl, a substituted or unsubstituted C 5-30 heteroaryl, or n n n n n n n n n n n n n n n n Where R′ and R″ are independently a substituted or unsubstituted aryl or a substituted or unsubstituted alkyl, wherein said compound is a vitamin D receptor (VDR) antagonist, a compound comprising same, and a method of treating a patient for a disease that can be treated prophylactically or therapeutically by administration of a VDR antagonist, which method comprises administering an effective amount of aforementioned compound or composition, whereupon the patient is treated prophylactically or therapeutically for the disease. |