http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7358053-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a3a6eba4b816ee1fc1a853b0b646e71 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-90 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2003-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_696099e9c16b6c72382cd1369c04627a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03614b90fae63d8fbce4147540afc802 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fc30139563fb6debf79cb05313ef837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_886370ddfc49a3b5a73077c873dad68d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d79394ebac3a1c0ed2da5f6cd6a57f19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49d9e24054f72f9d3f057f142a950118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_171cc05cdad18e03a03891e90e437962 |
| publicationDate | 2008-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7358053-B2 |
| titleOfInvention | Methods for detecting and reversing resistance to macrocyclic lactone compounds |
| abstract | This invention describes novel purified and isolated nucleic acid molecules or the fragments thereof, extracted from nematode or arthropod pests or recombinant, which encode P-glycoprotein homologs and regulate resistance to the macrocyclic lactone compounds. The invention further relates to the new P-glycoprotein homolog expression product of these nucleic acids. Also described herein are methods for detecting the gene encoding for resistance to the macrocyclic lactone compounds in nematode or arthropod pests which comprise comparing the nucleic acids extracted from a pest specimen to the nucleic acids encoding for resistance and the nucleic acids encoding for susceptibility to the macrocyclic lactone compounds. Lastly, the present invention is also drawn to methods and compositions for increasing the efficacy of the macrocyclic lactone compounds against resistant nematode or resistant arthropod pests which comprise administering to a mammal or applying to crops and the like a pesticidal enhancing effective amount of a multidrug resistance reversing agent. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008038832-A1 |
| priorityDate | 1997-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 180.