Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6572ff5df928fd17340eb2a8cb6d8502 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 |
filingDate |
2003-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2008-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fdcd08c184de339633ae9c65f211c07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7240115990564141d9dc6f0f1ca9bb01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64c1e44d2a4aabb2a4f1d654d460e607 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ce1bef7f9e4d74a435ac174c38fdc9a |
publicationDate |
2008-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7326794-B2 |
titleOfInvention |
Process for the preparation of high purity perindopril and intermediates useful in the synthesis |
abstract |
The invention relates to 1-{2(S)-[1(S)-(ethoxycarbonyl)butylamino]propionyl}-(3aS,7aS)octahydroindol-2(S)-carboxylic acid of the Formula I and the t-butylamine salt of the Formula I′ thereof free of contaminations derivable from dicyclohexyl carbodiimide, and a process for the preparation thereof. n The invention also relates to new intermediates of the general Formula III (wherein R stands for lower alkyl or aryl lower alkyl). n The compound of the Formula I—perindopril—is a known ACE inhibitor. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016178591-A2 |
priorityDate |
2002-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |